Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246793 | 0.80 | LMNA (0.41) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL8031525 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL13403334 | 0.72 | TSHR (0.44) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL8043146 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL11486063 | 0.69 | LMNA (0.49) | ALDH1A1LMNAEPHX1TYRRECQL | |
| SCHEMBL7761117 | 0.67 | SCN10A (0.46) | ALDH1A1LMNAKIF11TYRRECQL | |
| SCHEMBL17085961 | 0.67 | SCN10A (0.46) | ALDH1A1LMNAKIF11TYRRECQL | |
| SCHEMBL19867491 | 0.67 | KIF11 (0.47) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL11516166 | 0.67 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL19154876 | 0.66 | TSHR (0.42) | ALDH1A1MAPTNPSR1LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6639109-B1 | Reacting amino alcohol with sulfuric acid then reacting resulting amino sulfate with a mercaptan; simple, safe, rapid | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1216988-A1 | THIOALKYLAMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |