Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34474839 | 1.00 | ALDH1A1 (0.51) | ALDH1A1EPAS1RXFP1KDM4EHPGD | |
| SCHEMBL642859 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL28242926 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL751534 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL1050258 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL3198514 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL34475343 | 0.78 | GPR27 (0.60) | ALDH1A1RXFP1KDM4EHPGDKMT2A | |
| SCHEMBL10669297 | 0.77 | MAPT (0.60) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL11821095 | 0.76 | EPAS1 (0.46) | ALDH1A1EPAS1KDM4EHPGDMEN1 | |
| SCHEMBL5578273 | 0.76 | ALDH1A1 (0.64) | ALDH1A1EPAS1RXFP1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203941-A1 | Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus | WYETH (US) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203941-A1 | Substituted phenyl compounds for the treatment of non-insulin dependent diabetes mellitus | GPR119, INSR, SLC5A1 | ALDH1A1 536/4885EPAS1 979/4885RXFP1 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.