Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924288 | 0.78 | C1S (0.71) | PLAUC1SALDH1A1MAPTMEN1 | |
| SCHEMBL2326735 | 0.76 | HDAC6 (0.57) | ALDH1A1HPGDLMNAMAPTGAA | |
| SCHEMBL12396903 | 0.71 | OPRD1 (0.73) | OPRD1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL14234477 | 0.70 | ALDH1A1 (0.56) | OPRD1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL2325062 | 0.70 | OPRD1 (0.51) | OPRD1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL6928117 | 0.68 | PLAU (0.61) | PLAUC1SOPRD1ALDH1A1HPGD | |
| SCHEMBL10088561 | 0.68 | OPRD1 (0.49) | OPRD1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL2323109 | 0.68 | L3MBTL1 (0.53) | PLAUC1SOPRD1ALDH1A1HPGD | |
| SCHEMBL2328247 | 0.67 | OPRD1 (0.51) | OPRD1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL829766 | 0.67 | SLC9A1 (0.60) | ALDH1A1HPGDLMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562840-B1 | Non-peptidic inhibitors of proteolytic enzymes such as urokinase | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | disclosed |