Cgs-21680

Cgs-21680

SCHEMBL724684

CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)nc(NCCc4ccc(CCC(=O)O)cc4)nc32)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 9/20 1.00
ADORA3 P0DMS8 7/20 1.00
ADORA1 P30542 7/20 1.00
ADORA2B P29275 4/20 1.00
KDM4E B2RXH2 3/20 1.00
ALOX15 P16050 2/20 1.00
HSD17B10 Q99714 2/20 1.00
KMT2A Q03164 2/20 1.00
TSHR P16473 1/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C19 P33261 1/20 1.00
PMP22 Q01453 1/20 0.98
ATM Q13315 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cgs-21680 SCHEMBL12648395 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL13285993 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL14397691 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL3730487 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL2318561 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL724685 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL24178317 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL19807521 1.00 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL26629876 0.99 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E
Cgs-21680 SCHEMBL29381841 0.99 ADORA2A (1.00) ADORA2AADORA3ADORA1ADORA2BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 720 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262274-A1 Designed Biosensors for Enhanced T Cell Therapy ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) 2025-08-21 US claimed
CN-119969964-A Research method for influence on TBI post-impulse behavior 重庆医科大学 2025-05-13 CN claimed
CN-119838153-A Method for regulating and controlling lymphatic system and application thereof 温州医科大学附属眼视光医院 2025-04-18 CN claimed
EP-4526335-A1 DESIGNED BIOSENSORS FOR ENHANCED T CELL THERAPY Centre Hospitalier Universitaire Vaudois (CH) 2025-03-26 EP claimed
CN-119303086-A Pharmaceutical composition for treating autism 斯塔利克拉股份有限公司 2025-01-14 CN claimed
US-20240358663-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-10-31 US claimed
CN-118813543-A Multi-mode tracer three-reporter gene stem cell line, preparation method thereof, and brain tracer application and imaging system 浙江大学 2024-10-22 CN claimed
WO-2024215814-A2 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING AGING ANAND RENE (US) 2024-10-17 WO claimed
WO-2024182811-A1 COMPOSITIONS AND METHODS FOR TREATING UTERINE LEIOMYOMAS UNIVERSITY OF SOUTH FLORIDA (US) 2024-09-06 WO claimed
WO-2024168320-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING DEMENTIA ANAND RENE (US) 2024-08-15 WO claimed
US-11519008-B2 Exosome delivery system JOSLIN DIABETES CENTER (US) 2022-12-06 US claimed
EP-4051715-A1 DEGRADATION OF SURFACE PROTEINS USING BISPECIFIC BINDING AGENT The Regents of the University of California (US) 2022-09-07 EP claimed
CN-114867752-A Degradation of surface proteins using bispecific binders 加利福尼亚大学董事会 2022-08-05 CN claimed
US-20210106605-A1 Adenosine Receptor Modulators for the Treatment of Circadian Rhythm Disorders OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2021-04-15 US claimed
US-20190111069-A1 Adenosine Receptor Modulators for the Treatment of Circadian Rhythm Disorders OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2019-04-18 US claimed
US-20180344655-A1 FUNCTIONALIZED POLYMERIC PARTICLES FOR TREATMENT OF GLIOMAS YALE UNIVERSITY 2018-12-06 US claimed
EP-3280414-A1 ADENOSINE RECEPTOR MODULATORS FOR THE TREATMENT OF CIRCADIAN RHYTHM DISORDERS Oxford University Innovation Limited (GB) 2018-02-14 EP claimed
WO-2017178820-A1 ADENOSINE RECEPTOR MODULATORS FOR THE TREATMENT OF CIRCADIAN RHYTHM DISORDERS OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2017-10-19 WO claimed
WO-2016183217-A1 FUNCTIONALIZED POLYMERIC PARTICLES FOR TREATMENT OF GLIOMAS YALE UNIVERSITY (US) 2016-11-17 WO claimed
EP-0983768-A1 MEDICINAL COMPOSITION FOR PREVENTION OR TREATMENT OF HEPATOPATHY Nippon Shinyaku Co., Ltd. (JP) 2000-03-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358663-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION VASP, MYLK, EDNRB ADORA2A 7/4885ADORA3 59/4885ADORA1 68/4885
US-20210106605-A1 Adenosine Receptor Modulators for the Treatment of Circadian Rhythm Disorders ADORA2A, ADORA2B, ADORA3 ADORA2A 1/4885ADORA3 3/4885ADORA1 4/4885
US-20180344655-A1 FUNCTIONALIZED POLYMERIC PARTICLES FOR TREATMENT OF GLIOMAS PHLPP1, PHLPP2, PLAA ADORA2A 10/4885ADORA3 32/4885ADORA1 39/4885
US-20190111069-A1 Adenosine Receptor Modulators for the Treatment of Circadian Rhythm Disorders ADORA2A, ADORA2B, ADORA3 ADORA2A 1/4885ADORA3 3/4885ADORA1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.