Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7177046 | 1.00 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CKDM1AMAOA | |
| SCHEMBL7247234 | 1.00 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CKDM1AMAOA | |
| SCHEMBL2197644 | 0.85 | KDM1A (0.58) | KDM1AMAOAGRIN2BFUCA1BCHE | |
| SCHEMBL2936924 | 0.85 | KDM1A (0.58) | KDM1AMAOAGRIN2BFUCA1BCHE | |
| SCHEMBL491107 | 0.85 | KDM1A (0.58) | KDM1AMAOAGRIN2BFUCA1BCHE | |
| SCHEMBL2198525 | 0.85 | KDM1A (0.58) | KDM1AMAOAGRIN2BFUCA1BCHE | |
| SCHEMBL2798417 | 0.85 | KDM1A (0.58) | KDM1AMAOAGRIN2BFUCA1BCHE | |
| SCHEMBL2197651 | 0.85 | KDM1A (0.58) | KDM1AMAOAGRIN2BFUCA1BCHE | |
| SCHEMBL13636960 | 0.85 | KDM1A (0.47) | KDM1AMAOALTA4HGRIN2BFUCA1 | |
| SCHEMBL249579 | 0.85 | LTA4H (0.60) | KDM1AMAOALTA4HGRIN2BFUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | GOLDSTEIN STEVEN WAYNE (US) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191279-A1 | Urea derivatives useful as anticancer agents | CCNA1, CCNE1, CCND1 | ADRA2A 4469/4885ADRA2B 4009/4885ADRA2C 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.