Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630325 | 0.88 | MEN1 (0.63) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL8333913 | 0.86 | MEN1 (0.68) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL6656572 | 0.85 | OPRM1 (0.45) | — | |
| SCHEMBL4541225 | 0.85 | MEN1 (0.64) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL18792905 | 0.81 | MEN1 (0.63) | MEN1KMT2A | |
| SCHEMBL3111413 | 0.81 | MEN1 (0.65) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL3837667 | 0.80 | MEN1 (0.61) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL2792425 | 0.79 | MEN1 (0.60) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL3809403 | 0.78 | MEN1 (0.70) | MEN1KMT2AGPR119KDM4EPKM | |
| SCHEMBL652408 | 0.77 | MEN1 (0.57) | MEN1KMT2AGPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069276-A1 | Amino piperidine derivatives | CCR5, CCR2, CXCR4 | MEN1 4879/4885KMT2A 3009/4885GPR119 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.