SCHEMBL7247802

SCHEMBL7247802

CCc1ccc(Cc2c[nH]cn2)c(C)c1NS(=O)(=O)CC

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.33
HPGD P15428 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDE10A Q9Y233 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254139 0.91 HPGD (0.31) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL7248382 0.81 NR3C1 (0.41) HPGDLMNAHTTSMN1; SMN2PDE10A
SCHEMBL7254649 0.77
SCHEMBL7097637 0.76 BRD4 (0.32) HPGDLMNAHTTPDE10A
SCHEMBL7102580 0.76 HPGD (0.40) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL7248262 0.76 MEN1 (0.32)
SCHEMBL7248995 0.74 BRD4 (0.40) HPGDLMNAHTTSMN1; SMN2PDE10A
SCHEMBL7248295 0.74 PGR (0.37) HPGDLMNAHTTSMN1; SMN2MAPT
SCHEMBL7248476 0.74 BRAF (0.34) HPGDLMNAHTTPDE10A
SCHEMBL7103450 0.74 BRD4 (0.31) HTTPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6503935-B1 Treating urinary incontinence or retrograde ejaculation ABBOTT LABORATORIES 2003-01-07 US disclosed