Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276930 | 0.88 | USP30 (0.53) | GPR119USP30MAPTNPC1ALDH1A1 | |
| SCHEMBL2325199 | 0.81 | GPR119 (0.49) | GPR119USP30MAPTNPC1ALDH1A1 | |
| SCHEMBL2325204 | 0.81 | GPR119 (0.49) | GPR119USP30MAPTNPC1ALDH1A1 | |
| SCHEMBL2325193 | 0.81 | GPR119 (0.49) | GPR119USP30MAPTNPC1ALDH1A1 | |
| SCHEMBL3607879 | 0.80 | GPR119 (0.48) | GPR119USP30 | |
| SCHEMBL3607883 | 0.80 | GPR119 (0.48) | GPR119USP30 | |
| SCHEMBL7247703 | 0.78 | GPR119 (0.51) | GPR119USP30TRPV3KMT2A | |
| SCHEMBL377914 | 0.77 | ALDH1A1 (0.62) | GPR119MAPTNPC1ALDH1A1MAPK1 | |
| SCHEMBL12090855 | 0.76 | REN (0.54) | GPR119USP30 | |
| SCHEMBL3608984 | 0.76 | GPR119 (0.47) | GPR119USP30TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635661-B2 | Piperidinyl amide compounds | SEPRACOR INC. | 2003-10-21 | — | — | US | disclosed |
| US-20020016337-A1 | Heterocyclic analgesic compounds and methods of use thereof | SEPRACOR INC. | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016337-A1 | Heterocyclic analgesic compounds and methods of use thereof | OPRL1, TRPV1, OPRK1 | GPR119 697/4885USP30 3782/4885MAPT 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.