SCHEMBL7248282

SCHEMBL7248282

CN(C)c1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@@]2(C)O)c(=O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 9/20 0.57
▸ ADORA3 P0DMS8 11/20 0.51
▸ ADORA1 P30542 8/20 0.51
▸ ADORA2B P29275 4/20 0.51
▸ ADA P00813 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15459915 0.87 ADORA2A (0.60) ADORA2AADORA3ADORA1ADORA2BADA
SCHEMBL14583683 0.87 ADORA2A (0.60) ADORA2AADORA3ADORA1ADORA2BADA
SCHEMBL13559229 0.87 ADORA2A (0.60) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL10819905 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL21007207 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL15187539 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL12149502 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL18537392 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL14842089 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA
2'-B-Methyl-Guanosine SCHEMBL12758165 0.86 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109976-A1 SYNTHETIC ENGINEERED RNA MOLECULES AND RELATED METHODS RNAV8 BIO INC (US) 2026-04-23 — — US disclosed
US-20240139345-A1 NUCLEIC ACID VECTORS AND METHODS OF USE ALDEVRON, LLC 2024-05-02 — — US disclosed
WO-2023215516-A2 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES, INC. (US) 2023-11-09 — — WO disclosed
US-9770463-B2 Delivery of RNA to different cell types GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2017-09-26 — — US disclosed
US-20130195968-A1 VIRION-LIKE DELIVERY PARTICLES FOR SELF-REPLICATING RNA MOLECULES NOVARTIS AG (CH) 2013-08-01 — — US disclosed
US-20130177640-A1 DELIVERY OF RNA TO DIFFERENT CELL TYPES NOVARTIS AG (CH) 2013-07-11 — — US disclosed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109976-A1 SYNTHETIC ENGINEERED RNA MOLECULES AND RELATED METHODS UPF1, RNGTT, NSUN3 ADORA2A 3110/4885ADORA3 3580/4885ADORA1 4503/4885
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR ADORA2A 2315/4885ADORA3 1274/4885ADORA1 1280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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