SCHEMBL7248349

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28203968	0.73	ALDH1A1 (0.50)	ALDH1A1PGK1SMN1; SMN2ACHEKDM4E
	SCHEMBL7530707	0.72	ALDH1A1 (0.51)	ALDH1A1HSD17B10GAAMAPK1PGK1
	SCHEMBL8335123	0.72	HTR2A (0.51)	SMN1; SMN2
	SCHEMBL7059303	0.72	HTR2A (0.40)	ALDH1A1MAPK1CYP1A2SMN1; SMN2LMNA
	SCHEMBL7525330	0.72	ALDH1A1 (0.50)	ALDH1A1CASP3SENP8SENP7SENP6
	SCHEMBL30018702	0.69	PDE4A (0.46)	ALDH1A1HSD17B10PGK1SMN1; SMN2ACHE
	SCHEMBL5663443	0.69	KMT2A (0.51)	ALDH1A1HSD17B10GAAMAPK1CYP1A2
	SCHEMBL7531918	0.69	MAPT (0.59)	ALDH1A1GAAMAPK1SMN1; SMN2ACHE
	SCHEMBL13159618	0.69	ACHE (0.48)	ALDH1A1GAAMAPK1CRHR1ACHE
	SCHEMBL12963035	0.68	ALDH1A1 (0.42)	ALDH1A1GAAMAPK1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.