Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15847746 | 0.93 | PDE4B (0.32) | PDE4BCFTRKDM4CALDH1A1HTT | |
| SCHEMBL723761 | 0.92 | ALDH1A1 (0.34) | PDE4BALDH1A1RAB9A | |
| SCHEMBL20348684 | 0.90 | PDE4B (0.33) | PDE4B | |
| SCHEMBL27214700 | 0.86 | PDE4B (0.33) | PDE4BALDH1A1 | |
| SCHEMBL29864727 | 0.86 | PDE4B (0.33) | PDE4BALDH1A1 | |
| SCHEMBL17404505 | 0.85 | ALDH1A1 (0.35) | PDE4BCFTRKDM4CALDH1A1SMN1; SMN2 | |
| SCHEMBL29864441 | 0.85 | PDE4B (0.30) | PDE4B | |
| SCHEMBL27214701 | 0.85 | PDE4B (0.30) | PDE4B | |
| SCHEMBL18361929 | 0.83 | CNR2 (0.30) | — | |
| SCHEMBL31414646 | 0.83 | KDM4C (0.35) | PDE4BCFTRKDM4CSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647314-B1 | CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-05-24 | — | — | EP | disclosed |
| US-11505563-B2 | Metal-ligand complex, catalyst composition for ethylene-based polymerization including the same, and method for preparing ethylene-based polymer using the same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-11-22 | — | — | US | disclosed |
| EP-3730501-B1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE-BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2022-09-14 | — | — | EP | disclosed |
| EP-3356430-B1 | A POLYMERIZATION PROCESS FOR PRODUCING ETHYLENE BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3344694-B1 | FLEXIBLE CROSSLINKED CABLE INSULATION AND METHODS FOR MAKING FLEXIBLE CROSSLINKED CABLE INSULATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-05-18 | — | — | EP | disclosed |
| US-20220135599-A1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-05-05 | — | — | US | disclosed |
| US-11242422-B2 | Polymerizations for olefin-based polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-02-08 | — | — | US | disclosed |
| US-11155693-B2 | Flexible crosslinked cable insulation and methods for making flexible crosslinked cable insulation | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-10-26 | — | — | US | disclosed |
| CN-106459286-B | Catalyst system for olefin polymerization | 陶氏环球技术有限责任公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-108377649-B | Polymerization process for producing ethylene-based polymers | 陶氏环球技术有限责任公司 | 2021-04-23 | — | — | CN | disclosed |
| EP-2609123-A1 | PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR | Dow Global Technologies LLC (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20130144018-A1 | PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144018-A1 | PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144018-A1 | PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2491062-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | Dow Global Technologies LLC (US) | 2012-08-29 | — | — | EP | disclosed |
| WO-2012027448-A1 | PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011146044-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011146291-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242422-B2 | Polymerizations for olefin-based polymers | OSTC, PPOX, OCIAD1 | PDE4B 4849/4885CFTR 4524/4885KDM4C 1711/4885 |
| US-11505563-B2 | Metal-ligand complex, catalyst composition for ethylene-based polymerization including the same, and method for preparing ethylene-based polymer using the same | EPRS1, NOTUM, ELL | PDE4B 4773/4885CFTR 4723/4885KDM4C 782/4885 |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | PDE4B 4555/4885CFTR 4108/4885KDM4C 3264/4885 |
| US-20220135599-A1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | NOTUM, EPRS1, ESD | PDE4B 4772/4885CFTR 4617/4885KDM4C 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.