Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.49 |
| ▸ | NCF1 | P14598 | 4/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.49 |
| ▸ | HTR3B | O95264 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515845 | 0.73 | HTR6 (0.54) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL31521684 | 0.72 | KDR (0.68) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL5564182 | 0.72 | HTR6 (0.60) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL5124241 | 0.72 | KDR (0.68) | HTR6NCF1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL9128302 | 0.71 | KDR (0.66) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL16678873 | 0.71 | ALDH1A1 (0.52) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL5369146 | 0.68 | HTR6 (0.68) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL12510593 | 0.67 | HTR3E (0.54) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL18949726 | 0.67 | HTR3E (0.58) | HTR6NCF1HTR3EHTR3BHTR3A | |
| SCHEMBL29385724 | 0.66 | HTR6 (1.00) | HTR6NCF1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025155-A1 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES | NOVARTIS AG (CH) | 2012-03-01 | — | — | WO | disclosed |