Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256417 | 0.99 | F2 (0.43) | L3MBTL1F2KDM4EHSD17B10GAA | |
| SCHEMBL7243857 | 0.84 | F2 (0.54) | F2KDM4EHSD17B10GAAHDAC1 | |
| SCHEMBL7253523 | 0.84 | F2 (0.47) | F2GAAHDAC1HDAC6HDAC8 | |
| SCHEMBL7250212 | 0.82 | F2 (0.45) | L3MBTL1F2KDM4EHSD17B10GAA | |
| SCHEMBL7249842 | 0.81 | F2 (0.43) | F2HDAC1HDAC6HDAC8MAPT | |
| SCHEMBL7250244 | 0.81 | HTR2C (0.45) | F2HDAC1HDAC6HDAC8POLB | |
| SCHEMBL7252575 | 0.80 | THRB (0.44) | F2HDAC1HDAC6HCAR3HDAC8 | |
| SCHEMBL7249812 | 0.79 | PPARG (0.42) | F2HDAC1HDAC6HDAC8HTR2C | |
| SCHEMBL7249727 | 0.79 | F2 (0.41) | F2HDAC1HDAC6HDAC8MAPT | |
| SCHEMBL7248203 | 0.79 | F2 (0.42) | F2KDM4EHSD17B10GAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |