Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HAT1 | O14929 | 2/20 | 0.52 |
| ▸ | EP300 | Q09472 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251407 | 0.78 | HPGD (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7250903 | 0.75 | TSHR (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8348907 | 0.75 | TSHR (0.51) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL734047 | 0.73 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7851490 | 0.72 | HTT (0.88) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7675962 | 0.71 | MMP2 (0.63) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7646131 | 0.71 | SOS1 (0.75) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9825896 | 0.71 | SOS1 (0.75) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL27798635 | 0.71 | SOS1 (0.75) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL26186702 | 0.70 | KMT2A (0.85) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MELACURE THERAPEUTICS AB (SE) | 2003-10-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MC1R, MC5R, MC4R | MEN1 1200/4885KMT2A 1399/4885SMN1; SMN2 4503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.