Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978172 | 0.92 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7251104 | 0.88 | ALDH1A1 (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL451904 | 0.84 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL19582716 | 0.79 | LDHA (0.40) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8750517 | 0.79 | MGAM (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL453324 | 0.78 | GAA (0.68) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1291088 | 0.78 | — | — | |
| SCHEMBL9068041 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL14498321 | 0.77 | MGAM (0.31) | MGAMGAASIMGAM2 | |
| SCHEMBL741428 | 0.76 | ALDH1A1 (0.38) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632958-B1 | An alkene (1) is added to cyclopentenone (2) under the action of an alkyl lithium and an organic copper reagent to form an adduct, said adduct is reacted with e.g. a carboxylic anhydride (4) to obtain a prostaglandin derivative, which is | MITSUBISHI PHARMA CORPORATION (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1085012-A1 | PROCESS FOR PRODUCING PURIFIED PROSTAGLANDIN DERIVATIVE | Asahi Glass Co., Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |