SCHEMBL741428

SCHEMBL741428

CCC(=O)O[Si](C)(C)C.[NaH]

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
NAAA Q02083 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
FFAR3 O14843 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
SOAT1 P35610 1/20 0.32
HIF1A Q16665 2/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
BLM P54132 1/20 0.31
WRN Q14191 1/20 0.31
ESR1 P03372 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1291088 0.97
SCHEMBL30825208 0.94 ALDH1A1 (0.38) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL29834082 0.94 ALDH1A1 (0.38) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL7885704 0.86 ALDH1A1 (0.39) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL431579 0.80 ALDH1A1 (0.39) ALDH1A1NAAATDP1FFAR3MGAM
SCHEMBL10820885 0.77 ALDH1A1 (0.35) ALDH1A1NAAATDP1
SCHEMBL7071406 0.77 MGAM (0.39) ALDH1A1NAAAMGAMGAASI
SCHEMBL4303758 0.77 TSHR (0.45) ALDH1A1BLMKMT2A
SCHEMBL1978172 0.77 MGAM (0.41) ALDH1A1MGAMGAASIMGAM2
SCHEMBL430933 0.77 ALDH1A1 (0.41) ALDH1A1NAAATDP1FFAR3MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114985010-B Bionic protease and preparation method and application thereof 长沙理工大学 2024-02-27 CN claimed
US-20260044080-A1 COPOLYMER, PHOTOSENSITIVE RESIN COMPOSITION, RESIN CURED FILM, AND IMAGE DISPLAY ELEMENT RESONAC CORPORATION (JP) 2026-02-12 US disclosed
US-20240402273-A1 INFECTION DIAGNOSIS AND CHARACTERIZATION USING DIFFUSION AND RELAXATION EDITED PROTON NMR SPECTROSCOPY BRUKER BIOSPIN GMBH & CO. KG (DE) 2024-12-05 US disclosed
US-20240352542-A1 MEANS AND METHODS FOR DIAGNOSING A VIRAL INFECTION OR A DISEASE ASSOCIATED THEREWITH BRUKER BIOSPIN GMBH & CO. KG (DE) 2024-10-24 US disclosed
EP-4443159-A1 MEANS AND METHODS FOR DIAGNOSING A VIRAL INFECTION Bruker BioSpin GmbH & Co. KG (DE) 2024-10-09 EP disclosed
EP-4281768-A1 INFECTION DIAGNOSIS AND CHARACTERIZATION USING DIFFUSION AND RELAXATION EDITED PROTON NMR SPECTROSCOPY Bruker BioSpin MRI GmbH (DE) 2023-11-29 EP disclosed
US-20230295679-A1 PROCESS FOR PREPARING ALKYL POLYGLUCOSIDES, AND ALKYL POLYGLUCOSIDES OBTAINED ACCORDING TO THE PROCESS INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE (FR) 2023-09-21 US disclosed
EP-3438651-B1 USES OF MARKER SUBSTANCES NUMARES AG (DE) 2023-09-13 EP disclosed
CN-111999332-B Method for measuring melezitose content in honey by nuclear magnetic resonance hydrogen spectrometry 钛和中谱检测技术(江苏)有限公司 2023-06-09 CN disclosed
US-20230151372-A1 Composition and Method of Treatment for Heart Protection and Regeneration ACADEMIA SINICA (TW) 2023-05-18 US disclosed
EP-1639016-A1 CELLULOSE ETHERS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2006-03-29 EP disclosed
WO-2005071070-A2 SUBSTANCES DIRECTED AGAINST SPECIFIC SEQUENCE ESSENTIAL FOR HEPARANASE CATALYTIC ACTIVITY END USES THEREOF AS HEPARANASE INHIBITORS HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. (IL) 2005-08-04 WO disclosed
US-20050065738-A1 Methods and apparatus for characterizing polymeric mixtures PARIVID LLC (US) 2005-03-24 US disclosed
WO-2005026720-A1 METHODS AND APPARATUS FOR CHARACTERIZING POLYMERIC MIXTURES PARIVID LLC (US) 2005-03-24 WO disclosed
WO-2005000903-A1 CELLULOSE ETHERS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2005-01-06 WO disclosed
US-20020002302-A1 Process for carboxylation of naphthoic acid to naphthalene dicarboxylic acid MOSSI & GHISOLFI OVERSEAS, S.A. (LU) 2002-01-03 US disclosed
US-6329497-B1 ANTITUMOR AGENTS; VIRICIDES AGAINST HUMAN IMMUNODEFICIENCY VIRUS THE SCRIPPS RESEARCH INSTITUTE 2001-12-11 US disclosed
EP-0996458-A4 SANDRAMYCIN ANALOGS SCRIPPS RESEARCH INST (US) 2001-05-02 EP disclosed
EP-0996458-A1 SANDRAMYCIN ANALOGS The Scripps Research Institute (US) 2000-05-03 EP disclosed
WO-1998043663-A1 SANDRAMYCIN ANALOGS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020002302-A1 Process for carboxylation of naphthoic acid to naphthalene dicarboxylic acid DDC, NDC1, PCCA ALDH1A1 453/4885NAAA 19/4885TDP1 3572/4885
US-20260044080-A1 COPOLYMER, PHOTOSENSITIVE RESIN COMPOSITION, RESIN CURED FILM, AND IMAGE DISPLAY ELEMENT KDM2B, KDM1A, KDM3A ALDH1A1 166/4885NAAA 3978/4885TDP1 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.