Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.56 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545037 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL29903853 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL6114801 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL5367040 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL2514450 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL797638 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL6115276 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL6115301 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL6114960 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 | |
| SCHEMBL28561362 | 0.98 | KCNH2 (0.61) | KCNH2GPBAR1TLR8CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124770-A1 | COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE | BEIJING NORMAL UNIVERSITY (CN) | 2024-04-18 | — | — | US | claimed |
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | claimed |
| WO-2022166889-A1 | COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE | 北京师范大学 | 2022-08-11 | — | — | WO | claimed |
| CN-113929623-A | Synthesis method of 2-arylquinoline compound | 温州医科大学附属口腔医院 | 2022-01-14 | — | — | CN | claimed |
| CN-112979713-A | Compound, light-emitting layer guest material, organic electroluminescent device and display device | 北京师范大学 | 2021-06-18 | — | — | CN | claimed |
| CN-111471009-A | Preparation method and application of 2-arylquinoline derivative | 安阳师范学院 | 2020-07-31 | — | — | CN | claimed |
| US-10629827-B2 | Organometallic complexes as phosphorescent emitters in organic LEDs | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-04-21 | — | — | US | claimed |
| CN-110467568-A | A kind of synthetic method of aryl quinoline derivatives | UNIV WENZHOU | 2019-11-19 | — | — | CN | claimed |
| CN-110461159-A | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG | 2019-11-15 | — | — | CN | claimed |
| CN-109715628-A | Novel Mesoionic Insecticidal Compounds | 日本化药株式会社 | 2019-05-03 | — | — | CN | claimed |
| US-20040262576-A1 | Organometallic complexes as phosphorescent emitters in organic LEDs | THOMPSON MARK E (US) | 2004-12-30 | — | — | US | claimed |
| CN-1531758-A | Polymer containing linked luminescent metal complexes and devices made from such polymers | E��I�����¶��Ű˾ | 2004-09-22 | — | — | CN | claimed |
| US-20040072018-A1 | Metallic complexes covalently bound to conjugated polymers and electronic devices containing such compositions | LG CHEM, LTD. (KR) | 2004-04-15 | — | — | US | claimed |
| WO-2004015025-A1 | METALLIC COMPLEXES COVALENTLY BOUND TO CONJUGATED POLYMERS AND ELECTRONIC DEVICES CONTAINING SUCH COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-02-19 | — | — | WO | claimed |
| EP-1364419-A2 | POLYMERS HAVING ATTACHED LUMINESCENT METAL COMPLEXES AND DEVICES MADE WITH SUCH POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-11-26 | — | — | EP | claimed |
| US-20030148142-A1 | Polymers having attached luminescent metal complexes and devices made with such polymers | LG CHEM, LTD. (KR) | 2003-08-07 | — | — | US | claimed |
| WO-2002031896-A2 | POLYMERS HAVING ATTACHED LUMINESCENT METAL COMPLEXES AND DEVICES MADE WITH SUCH POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-18 | — | — | WO | claimed |
| US-5856337-A | 2-arylquinolines and process for producing the same | ASAHI GLASS CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| EP-0786460-A2 | 2-Arylquinolines and process for producing the same | ASAHI GLASS COMPANY LTD. (JP) | 1997-07-30 | — | — | EP | claimed |
| WO-1994002145-A2 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10629827-B2 | Organometallic complexes as phosphorescent emitters in organic LEDs | MLX, L1CAM, POU5F1 | KCNH2 193/4885GPBAR1 4797/4885TLR8 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.