SCHEMBL725197

SCHEMBL725197

O=C1CC(c2ccccc2)c2cc(Br)ccc2O1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
HPGD P15428 3/20 0.70
GAA P10253 1/20 0.70
HSD17B10 Q99714 1/20 0.70
SIRT2 Q8IXJ6 8/20 0.64
ALDH2 P05091 1/20 0.58
GLA P06280 1/20 0.52
CYP19A1 P11511 1/20 0.51
SIRT1 Q96EB6 1/20 0.51
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9228116 0.82 ALDH1A1 (0.70) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL5269737 0.82 ALDH1A1 (0.79) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL820663 0.82 ALDH1A1 (0.79) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL12856664 0.82 ALDH1A1 (0.70) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL5269218 0.82 ALDH1A1 (0.79) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL14852665 0.81 ALDH1A1 (0.68) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL12200287 0.81 ALDH1A1 (0.68) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL12200316 0.81 ALDH1A1 (0.68) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL9223130 0.81 ALDH1A1 (0.68) ALDH1A1HPGDGAAHSD17B10SIRT2
SCHEMBL14430966 0.80 ALDH1A1 (0.71) ALDH1A1HPGDGAAHSD17B10SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US claimed
US-20130197260-A1 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2013-08-01 US claimed
WO-2012098560-A2 PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST MSN LABORATORIES LIMITED (IN) 2012-07-26 WO claimed
WO-2012025941-A2 PROCESSES FOR THE PREPARATION OF FESOTERODINE CADILA HEALTHCARE LIMITED (IN) 2012-03-01 WO claimed
EP-2545024-B1 PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-SUBSTITUTED PHENYL)-3-PHENYLPROPYLAMINES, INTERMEDIATES FOR MAKING HYDROXYTOLTERODINE AND FESOTERODINE LEK PHARMACEUTICALS (SI) 2016-08-03 EP disclosed
US-9085509-B2 Process for preparing fesoterodine ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-07-21 US disclosed
US-9085509-B2 Process for preparing fesoterodine ALEMBIC PHARMACEUTICALS LIMITED (IN) 2015-07-21 US disclosed
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US disclosed
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US disclosed
US-9012678-B2 Processes for the preparation of fesoterodine CADILA HEALTHCARE LIMITED (IN) 2015-04-21 US disclosed
US-8728705-B2 Negative photosensitive material, photosensitive board employing the negative photosensitive material, and negative pattern forming method NITTO DENKO CORPORATION (JP) 2014-05-20 US disclosed
US-8722920-B2 Process for obtaining 3, 3-diphenylpropylamines CRYSTAL PHARMA S.A.U. (ES) 2014-05-13 US disclosed
WO-1999058478-A1 NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES SCHWARZ PHARMA AG (DE) 1999-11-18 WO disclosed
EP-0957073-A1 Novel derivatives of 3,3-diphenylpropylamines SCHWARZ PHARMA AG (DE) 1999-11-17 EP disclosed
EP-0667852-B1 NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION PHARMACIA & UPJOHN AB (SE) 1998-04-08 EP disclosed
US-5686464-A ANTICHOLINERGIC AGENTS; URINARY INCONTINENCE TREATMENT PHARMACIA AB (SE) 1997-11-11 US disclosed
US-5559269-A ANTICHOLINERGIC AGENTS PHARMACIA AB (SE) 1996-09-24 US disclosed
EP-0667852-A1 NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION Pharmacia & Upjohn Aktiebolag (SE) 1995-08-23 EP disclosed
WO-1994011337-A9 NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION 1995-07-06 WO disclosed
WO-1994011337-A1 NOVEL 3,3-DIPHENYLPROPYLAMINES, THEIR USE AND PREPARATION PHARMACIA AB (SE) 1994-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197260-A1 PROCESSES FOR THE PREPARATION OF FESOTERODINE QDPR, FES, SULT1A1 ALDH1A1 849/4885HPGD 1750/4885GAA 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.