Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028328 | 0.92 | TERT (0.49) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7242175 | 0.85 | TERT (0.56) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL7251982 | 0.85 | TERT (0.43) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL6781951 | 0.83 | KDM4E (0.60) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL6781638 | 0.83 | TERT (0.61) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL6790891 | 0.82 | KDM4E (0.59) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL6786762 | 0.80 | KDM4E (0.53) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL6787614 | 0.80 | KDM4E (0.53) | KDM4EKMT2AALDH1A1HPGDPOLB | |
| SCHEMBL7248045 | 0.79 | TERT (0.41) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7241600 | 0.78 | TERT (0.57) | KDM4EKMT2AALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660764-B2 | Telomerase inhibitors such as trans-3-(benzothien-6-yl)-but-2-enoic acid-N-(2-carboxy-phenyl)-amide; use as antitumor agent | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-12-09 | — | — | US | disclosed |
| US-20020123509-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and the preparation thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-09-05 | — | — | US | disclosed |
| WO-2002051830-A1 | CARBOXAMIDES FOR USE AS TELOMERASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123509-A1 | Carboxylic acid amides, pharmaceutical compositions containing these compounds, their use and the preparation thereof | ASS1, ADCY1, ADCY3 | KDM4E 2061/4885KMT2A 2342/4885ALDH1A1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.