SCHEMBL9620180

SCHEMBL9620180

COC(=O)C(N)c1ccc(N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.42
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAOA P21397 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HTT P42858 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
ADRB2 P07550 2/20 0.37
ADRB1 P08588 2/20 0.37
ADRB3 P13945 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7252180 0.92 KMT2A (0.48) SLC6A3KMT2ACYP1A2CYP3A4ALDH1A1
SCHEMBL14032514 0.88 L3MBTL1 (0.46) KMT2ALMNAALDH1A1KDM4EHTT
SCHEMBL8252300 0.84 L3MBTL1 (0.45) KMT2ALMNAALDH1A1ESR1ESR2
SCHEMBL2585312 0.84 ESR1 (0.54) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL1143624 0.84 ESR1 (0.54) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL1143625 0.84 ESR1 (0.54) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL8058922 0.84 L3MBTL1 (0.45) KMT2ALMNAALDH1A1ESR1ESR2
SCHEMBL3504026 0.82 CYP1A2 (0.48) KMT2ALMNACYP1A2ALDH1A1MAPT
SCHEMBL1969493 0.82 RAB9A (0.49) KMT2ACYP1A2RAB9A
SCHEMBL21787640 0.82 SLC6A3 (0.46) SLC6A3KMT2AALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE33948-E Bactericides, animal growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
US-4748163-A Novel β-lactam antibiotics BAYER AKTIENGESELLSCHAFT (DE) 1988-05-31 US disclosed