Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.82 |
| ▸ | PPARA | Q07869 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644316 | 0.90 | PPARG (1.00) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1308769 | 0.90 | PPARG (0.69) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14363391 | 0.83 | PPARG (0.66) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2891026 | 0.82 | PPARG (0.68) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13964448 | 0.82 | HDAC1 (0.72) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1307242 | 0.82 | PPARG (0.81) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2270596 | 0.81 | ACLY (0.70) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL11604086 | 0.80 | CLCN2 (0.61) | PPARGPPARARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1308314 | 0.79 | GRIK1 (0.69) | PPARGPPARASMN1; SMN2MAPTLMNA | |
| SCHEMBL2681276 | 0.79 | RAB9A (0.69) | PPARGPPARARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | claimed |