Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | PPARA | Q07869 | 1/20 | 0.68 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.58 |
| ▸ | OXTR | P30559 | 1/20 | 0.58 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.58 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308769 | 0.89 | PPARG (0.69) | PPARGPPARAGRIK1ALDH1A1MAPT | |
| SCHEMBL1308314 | 0.88 | GRIK1 (0.69) | PPARGPPARAGRIK1ALDH1A1MAPT | |
| SCHEMBL1307242 | 0.88 | PPARG (0.81) | PPARGPPARATP53ALDH1A1MAPT | |
| SCHEMBL2270596 | 0.86 | ACLY (0.70) | PPARGPPARAGRIK1SUCNR1KDM4E | |
| SCHEMBL9901505 | 0.86 | CYP2C19 (0.72) | PPARGPPARAGRIK1TP53ALDH1A1 | |
| SCHEMBL1514283 | 0.85 | HPGD (0.77) | ALDH1A1MAPTLMNARAB9ACYP2C19 | |
| SCHEMBL7038130 | 0.85 | SERPINE1 (0.70) | PPARGPPARAGRIK1TP53SUCNR1 | |
| SCHEMBL7040843 | 0.83 | PPARG (0.69) | PPARGPPARATP53SUCNR1KDM4E | |
| SCHEMBL2364731 | 0.83 | SRC (0.58) | PPARGPPARAGRIK1TP53ALDH1A1 | |
| SCHEMBL2270119 | 0.83 | PPARG (0.64) | PPARGPPARAGRIK1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017044551-A1 | PPAR-ALPHA AGONISTS FOR TREATING MITOCHONDRIAL DISEASES | MITOBRIDGE, INC. (US) | 2017-03-16 | — | — | WO | disclosed |
| US-20100286215-A1 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286215-A1 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | LTC4S, LTB4R2, LTB4R | PPARG 536/4885PPARA 1075/4885GRIK1 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.