SCHEMBL7253171

SCHEMBL7253171

CCOC(CC)COC=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254295 0.83
SCHEMBL7250184 0.83
SCHEMBL8903577 0.83
SCHEMBL7252395 0.79 DNM1 (0.37)
SCHEMBL7247221 0.79
SCHEMBL15199873 0.79 CTSK (0.30)
SCHEMBL12237534 0.78 ALDH1A1 (0.32)
SCHEMBL27718001 0.76 THRB (0.35) THRBLMNA
SCHEMBL7249096 0.76
SCHEMBL7254653 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602825-B1 Cyclization of an isocyanate with a thiourea and carbonic acid BASF AKTIENGESELLSCHAFT (DE) 2003-08-05 US disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
EP-0275381-B1 DYE TRANSFER PROCESS BASF Aktiengesellschaft (DE) 1992-03-04 EP disclosed
EP-0275381-A2 Dye transfer process BASF Aktiengesellschaft (DE) 1988-07-27 EP disclosed
US-4760049-A Dye transfer BASF AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed