Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10027324 | 1.00 | TSHR (0.36) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 | |
| SCHEMBL8724684 | 0.84 | ADRB2 (0.45) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 | |
| SCHEMBL8724680 | 0.84 | ADRB2 (0.45) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 | |
| SCHEMBL968217 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL968216 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL28910378 | 0.82 | TSHR (0.36) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 | |
| SCHEMBL4464674 | 0.80 | ALDH1A1 (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL14724824 | 0.79 | ADRB2 (0.41) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL11918809 | 0.78 | CYP3A4 (0.37) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 | |
| SCHEMBL20239708 | 0.77 | TSHR (0.33) | TSHRCYP3A4ALDH1A1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642306-B1 | In situ addition polymerization in the presence of azocarboxylic acid ester initiator | ATOFINA (FR) | 2003-11-04 | — | — | US | disclosed |