Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL2396169 | 1.00 | CA5A (0.47) | CA5ACA5BALDH1A1TDP1MAPT | |
| Trolamine SCHEMBL9299420 | 0.97 | CA5A (0.44) | CA5ACA5BALDH1A1TDP1MAPT | |
| Trolamine SCHEMBL9300209 | 0.95 | CA5A (0.42) | CA5ACA5BALDH1A1TDP1MAPT | |
| Trolamine SCHEMBL3283293 | 0.90 | CA5A (0.38) | CA5ACA5BALDH1A1TDP1MAPT | |
| Nitric Acid SCHEMBL1832473 | 0.84 | ALDH1A1 (0.40) | CA5ACA5BALDH1A1MAPTKDM4E | |
| Nitric Acid SCHEMBL8445719 | 0.83 | CA5A (0.42) | CA5ACA5BALDH1A1TDP1KDM4E | |
| Nitric Acid SCHEMBL9007438 | 0.82 | ALDH1A1 (0.33) | CA5ACA5BALDH1A1TDP1MAPT | |
| Nitric Acid SCHEMBL11831019 | 0.82 | POLB (0.34) | CA5ACA5BALDH1A1TDP1MAPT | |
| Nitric Acid SCHEMBL11756902 | 0.82 | POLB (0.34) | CA5ACA5BALDH1A1TDP1MAPT | |
| Trolamine SCHEMBL3283288 | 0.82 | TDP1 (0.40) | CA5ACA5BALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798017-A | Formula and preparation method of underground mine blasting mixed emulsion explosive | 贵州大学 | 2025-04-11 | — | — | CN | claimed |
| CN-119638590-A | Organic micromolecular gelatinizer and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2025-03-18 | — | — | CN | claimed |
| CN-114152582-A | Method for analyzing uranium by using absolute ethyl alcohol-aqueous medium | 中核通辽铀业有限责任公司 | 2022-03-08 | — | — | CN | claimed |
| CN-108488005-B | Thrust-controllable multi-pulse solid rocket engine | 重庆大学 | 2020-02-07 | — | — | CN | claimed |
| CN-110643399-A | High-energy oxygen-containing liquid fuel | 张繁荣 | 2020-01-03 | — | — | CN | claimed |
| CN-108488005-A | A kind of multiple-pulse solid propellant rocket of thrust controllable | 重庆大学 | 2018-09-04 | — | — | CN | claimed |
| EP-2714264-B1 | CATALYST, GAS GENERATOR, AND THRUSTER WITH IMPROVED THERMAL CAPABILITY AND CORROSION RESISTANCE | AEROJET ROCKETDYNE INC (US) | 2018-05-02 | — | — | EP | claimed |
| CN-106542942-A | A kind of boracic fuel-rich electric ignition solid propellant and preparation method thereof | 重庆大学 | 2017-03-29 | — | — | CN | claimed |
| CN-106495972-A | A kind of electric ignition solid propellant of fuel-rich containing aluminum and preparation method thereof | 重庆大学 | 2017-03-15 | — | — | CN | claimed |
| CN-106478323-A | Automatically controlled solid propellant of a kind of high-performance and preparation method thereof | 重庆大学 | 2017-03-08 | — | — | CN | claimed |
| US-5703323-A | Pyridine and pyridone stabilizers for hydroxylammonium nitrate and hydroxylamine-containing compositions | OLIN CORPORATION (US) | 1997-12-30 | — | — | US | claimed |
| EP-0785916-A1 | AN EXPLOSIVE COMPOSITION | DANTEX EXPLOSIVES (PROPRIETARY) LIMITED (ZA) | 1997-07-30 | — | — | EP | claimed |
| EP-0776797-A2 | Liquid-fueled inflator with a porous containment device | MORTON INTERNATIONAL, INC. (US) | 1997-06-04 | — | — | EP | claimed |
| US-5607181-A | Liquid-fueled inflator with a porous containment device | MORTON INTERNATIONAL, INC. (US) | 1997-03-04 | — | — | US | claimed |
| WO-1996011172-A1 | AN EXPLOSIVE COMPOSITION | DANTEX EXPLOSIVES (PROPRIETARY) LIMITED (ZA) | 1996-04-18 | — | — | WO | claimed |
| US-5507892-A | Explosive composition suitable for cartridging in paper and its method of manufacture | UNION ESPANOLA DE EXPLOSIVOS, SOCIEDAD ANONIMA (ES) | 1996-04-16 | — | — | US | claimed |
| US-5485722-A | Catalytic decomposition of hydroxylammonium nitrate-based monopropellants | OLIN CORPORATION (US) | 1996-01-23 | — | — | US | claimed |
| EP-0622346-A1 | Explosive composition suitable for cartridging in paper and its method of manufacture | UNION ESPANOLA DE EXPLOSIVOS S.A. (ES) | 1994-11-02 | — | — | EP | claimed |
| US-5014623-A | Binary munition system | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1991-05-14 | — | — | US | claimed |
| US-4946521-A | SAFE IN STORAGE AND MATERIAL HANDLING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1990-08-07 | — | — | US | claimed |