Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA8 | P11142 | 3/20 | 0.66 |
| ▸ | HSPA5 | P11021 | 3/20 | 0.66 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | GAPDH | P04406 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HBB | P68871 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254002 | 1.00 | HSPA8 (0.66) | HSPA8HSPA5PDE4APDE4BPDE4C | |
| SCHEMBL6761778 | 0.83 | HSPA8 (0.73) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL6761772 | 0.83 | HSPA8 (0.73) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL472569 | 0.83 | HSPA8 (0.72) | HSPA8HSPA5RXFP1SLC29A1GAPDH | |
| SCHEMBL472571 | 0.83 | HSPA8 (0.72) | HSPA8HSPA5RXFP1SLC29A1GAPDH | |
| SCHEMBL7258733 | 0.80 | HSPA8 (0.68) | HSPA8HSPA5RXFP1GAPDHHSD17B10 | |
| SCHEMBL1145052 | 0.80 | HSPA8 (1.00) | HSPA8HSPA5RXFP1SLC29A1GAPDH | |
| SCHEMBL17412455 | 0.80 | HSPA8 (1.00) | HSPA8HSPA5RXFP1SLC29A1GAPDH | |
| SCHEMBL1145049 | 0.80 | HSPA8 (1.00) | HSPA8HSPA5RXFP1SLC29A1GAPDH | |
| SCHEMBL13835110 | 0.79 | GAPDH (0.70) | HSPA8HSPA5PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |