Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257843 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7022294 | 0.81 | PTGS2 (0.45) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL7254588 | 0.79 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL7255519 | 0.71 | KDM4E (0.43) | PTGS2ALDH1A1PTGS1AR | |
| SCHEMBL7254182 | 0.70 | PTGS2 (0.40) | PTGS2ALDH1A1PTGS1AR | |
| SCHEMBL7257818 | 0.69 | PTGS1 (0.41) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL8112979 | 0.69 | PTGS2 (0.68) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL25372606 | 0.69 | LMNA (0.44) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27829594 | 0.67 | LMNA (0.43) | ALDH1A1 | |
| SCHEMBL10954891 | 0.67 | MAPK14 (0.61) | MAPK13MAPK12MAPK11MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006451-A1 | 4-PHENYLPYRAN-2-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2003-01-23 | — | — | WO | disclosed |