Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | SIK1 | P57059 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.38 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266954 | 0.89 | PDE4C (0.42) | METTTKCSF1RPRKAB2ABL1 | |
| SCHEMBL725161 | 0.79 | PDE4C (0.42) | METTTKPDE4CFEN1IKBKE | |
| SCHEMBL15209542 | 0.79 | MET (0.40) | METTTKCSF1RPRKAB2ABL1 | |
| SCHEMBL722554 | 0.78 | KDM4E (0.44) | PDE4C | |
| SCHEMBL721506 | 0.78 | PDE4C (0.39) | CSF1RPRKAB2ABL1LYNPRKAG1 | |
| SCHEMBL723546 | 0.76 | JAK2 (0.44) | CSF1RPRKAB2PRKAG1PRKAA1FGFR3 | |
| SCHEMBL724725 | 0.75 | PRKAB2 (0.42) | CSF1RPRKAB2ABL1LYNPRKAG1 | |
| SCHEMBL722258 | 0.75 | JAK2 (0.39) | TTKFGFR3FGFR1KDRFGFR2 | |
| SCHEMBL722228 | 0.74 | PDE4C (0.43) | METTTKPDE4CSYK | |
| SCHEMBL723668 | 0.74 | PGK1 (0.41) | PDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609100-A2 | FUROPYRIDINE DERIVATIVES | Merck Patent GmbH (DE) | 2013-07-03 | — | — | EP | claimed |
| WO-2012025187-A2 | FUROPYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | claimed |