Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 8/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812867 | 0.71 | CHRNB2 (0.52) | CHRNB2CHRNA4SLC6A4DRD2EGFR | |
| SCHEMBL28607372 | 0.68 | DRD2 (0.43) | SLC6A4DRD2KDM1AEGFRERBB2 | |
| SCHEMBL13535359 | 0.66 | SLC6A4 (0.46) | SLC6A4DRD2KDM1AEGFRERBB2 | |
| SCHEMBL15826853 | 0.66 | SLC6A4 (0.46) | SLC6A4DRD2KDM1AEGFRERBB2 | |
| SCHEMBL12648041 | 0.66 | SLC6A4 (0.46) | SLC6A4DRD2KDM1AEGFRERBB2 | |
| SCHEMBL13535357 | 0.66 | SLC6A4 (0.46) | SLC6A4DRD2KDM1AEGFRERBB2 | |
| SCHEMBL6684881 | 0.65 | KDM1A (0.53) | SLC6A4DRD2KDM1ASLC6A2SLC6A3 | |
| SCHEMBL3311195 | 0.65 | SLC6A4 (0.45) | SLC6A4DRD2KDM1ASLC6A2SLC6A3 | |
| SCHEMBL7256238 | 0.65 | DRD2 (0.69) | SLC6A4DRD2KDM1AMTNR1A | |
| SCHEMBL30465966 | 0.65 | SLC6A4 (0.46) | SLC6A4DRD2KDM1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642228-B1 | Treating ocular tension, carcinoma, sarcoma, tumentia, circulatory disease, or hypertension | TORAY INDUSTRIES, INC. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1106605-A1 | ALPHA1B-ADRENERGIC RECEPTOR ANTAGONISTS | TORAY INDUSTRIES, INC. (JP) | 2001-06-13 | — | — | EP | disclosed |