Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633248 | 0.97 | LMNA (0.35) | LMNAHTTSMN1; SMN2CTSSPTPN2 | |
| SCHEMBL7259162 | 0.85 | ALDH1A1 (0.40) | PTPN2PTPN1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL6630204 | 0.83 | ALDH1A1 (0.39) | PTPN2PTPN1ALDH1A1 | |
| SCHEMBL6632750 | 0.83 | ALDH1A1 (0.39) | PTPN2PTPN1ALDH1A1 | |
| SCHEMBL6632745 | 0.83 | ALDH1A1 (0.39) | PTPN2PTPN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7255797 | 0.81 | CTSS (0.47) | LMNAHTTSMN1; SMN2CTSSALDH1A1 | |
| SCHEMBL7260348 | 0.80 | CTSS (0.35) | LMNAHTTSMN1; SMN2CTSSALDH1A1 | |
| SCHEMBL6700659 | 0.80 | CTSS (0.35) | LMNAHTTSMN1; SMN2CTSSPTPN2 | |
| SCHEMBL6700654 | 0.80 | CTSS (0.35) | LMNAHTTSMN1; SMN2CTSSPTPN2 | |
| SCHEMBL6633244 | 0.80 | CTSS (0.35) | LMNAHTTSMN1; SMN2CTSSPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000838-A1 | PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |