Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255683 | 0.80 | LMNA (0.36) | CTSSLMNASMN1; SMN2HTTMAPT | |
| SCHEMBL7260343 | 0.78 | CTSS (0.32) | CTSSLMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL6633248 | 0.78 | LMNA (0.35) | CTSSLMNASMN1; SMN2HTTMAPT | |
| SCHEMBL6630258 | 0.76 | MAPT (0.39) | MAPTCYP3A4 | |
| SCHEMBL6061967 | 0.74 | CTSS (0.46) | CTSS | |
| SCHEMBL6063534 | 0.73 | CTSS (0.38) | CTSSLMNASMN1; SMN2HTTTSHR | |
| SCHEMBL6206920 | 0.72 | CTSS (0.41) | CTSSLMNASMN1; SMN2HTTTSHR | |
| SCHEMBL6061894 | 0.71 | FAAH (0.42) | CTSSLMNASMN1; SMN2HTTTSHR | |
| SCHEMBL6062624 | 0.71 | FAAH (0.42) | CTSSLMNASMN1; SMN2HTTTSHR | |
| SCHEMBL7259493 | 0.70 | CTSS (0.45) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000838-A1 | PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |