Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255703 | 0.79 | CA12 (0.54) | RAB9AL3MBTL1TP53ALOX15MEN1 | |
| SCHEMBL7259134 | 0.79 | ALPL (0.54) | POLBRAB9AL3MBTL1LMNAALOX15 | |
| SCHEMBL27604947 | 0.79 | MAPT (0.54) | RAB9ATP53LMNAALOX15MEN1 | |
| SCHEMBL528220 | 0.76 | POLB (0.53) | POLBRAB9AL3MBTL1TP53LMNA | |
| SCHEMBL1230353 | 0.76 | RAB9A (1.00) | POLBRAB9AL3MBTL1TP53LMNA | |
| SCHEMBL12472668 | 0.76 | RAB9A (0.63) | POLBRAB9AL3MBTL1TP53LMNA | |
| SCHEMBL6231163 | 0.75 | RAB9A (0.79) | POLBRAB9ALMNAALOX15MEN1 | |
| SCHEMBL24566759 | 0.74 | POLB (0.61) | POLBRAB9AL3MBTL1TP53LMNA | |
| SCHEMBL9277398 | 0.74 | POLB (0.61) | POLBRAB9AL3MBTL1TP53LMNA | |
| SCHEMBL8795650 | 0.74 | POLB (0.61) | POLBRAB9AL3MBTL1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080616-A1 | PYRAZOLOPYRIDAZINE DERIVATIVES, PROCESS FOR PREPARATION AND USE FOR THE INHIBITION OF GSK-3 | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |
| EP-2712616-B1 | Intermediates for the preparation of 1-(acetyl)-piperidine and 1-(acetyl)-piperazine derivatives as fungicides for use in plant protection | DU PONT (US) | 2017-04-19 | — | — | EP | disclosed |