Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255703 | 0.80 | CA12 (0.54) | ALPLMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7255684 | 0.79 | POLB (0.61) | ALPLMEN1KMT2ALMNARAB9A | |
| SCHEMBL2766145 | 0.79 | RAB9A (0.71) | ALPLMEN1KMT2ALMNARAB9A | |
| SCHEMBL6263733 | 0.78 | RAB9A (0.61) | MEN1KMT2ALMNARAB9ANPC1 | |
| SCHEMBL1143959 | 0.76 | ALPL (0.54) | ALPLMEN1KMT2ALMNARAB9A | |
| SCHEMBL28092499 | 0.73 | ALPL (0.56) | ALPLMEN1KMT2ALMNARAB9A | |
| SCHEMBL15006266 | 0.73 | ALPL (0.51) | ALPLMEN1KMT2ALMNARAB9A | |
| SCHEMBL31371407 | 0.73 | ALPL (0.51) | ALPLMEN1KMT2ALMNARAB9A | |
| SCHEMBL28903794 | 0.73 | CHEK1 (0.54) | ALPLLMNARAB9ANPC1MAPT | |
| SCHEMBL6566494 | 0.73 | RAB9A (0.48) | ALPLMEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080616-A1 | PYRAZOLOPYRIDAZINE DERIVATIVES, PROCESS FOR PREPARATION AND USE FOR THE INHIBITION OF GSK-3 | GLAXO GROUP LIMITED (GB) | 2003-10-02 | — | — | WO | claimed |