Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685628 | 0.85 | HRH4 (0.51) | HRH4TRPA1HRH3HTR6MAPT | |
| Hydrochloric Acid SCHEMBL5606159 | 0.84 | HRH4 (0.50) | HRH4TRPA1HRH3HTR6MAPT | |
| SCHEMBL5971687 | 0.82 | KDM4E (0.46) | HRH4TRPA1HRH3HTR6KDM4E | |
| SCHEMBL4780428 | 0.80 | ADRB1 (0.48) | TRPA1HTR6KDM4EALDH1A1TSHR | |
| SCHEMBL4187521 | 0.80 | DRD2 (0.48) | HTR6KDM4E | |
| SCHEMBL5972036 | 0.77 | DRD2 (0.48) | TRPA1HRH3HTR6KDM4EALDH1A1 | |
| SCHEMBL9091037 | 0.77 | DRD2 (0.51) | KDM4EALDH1A1MAPTPOLBGAA | |
| SCHEMBL9081200 | 0.76 | KDM4E (0.55) | KDM4E | |
| SCHEMBL9081701 | 0.76 | KDM4E (0.55) | KDM4E | |
| SCHEMBL9081524 | 0.76 | KDM4E (0.55) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135042-A1 | Atypical antipsychotic agents having low affinity for the D2 Receptor | NEUROMOLECULAR, INC. (CA) | 2003-07-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135042-A1 | Atypical antipsychotic agents having low affinity for the D2 Receptor | OPRD1, HTR1A, DRD2 | HRH4 528/4885TRPA1 2124/4885HRH3 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.