Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | SMO | Q99835 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227102 | 0.86 | LMNA (0.44) | SSTR5SMODRD4DRD2DRD3 | |
| SCHEMBL7262116 | 0.85 | SMO (0.45) | SSTR5PTGS1PTGS2SMODRD4 | |
| SCHEMBL7257441 | 0.85 | SSTR5 (0.42) | SSTR5PTGS1PTGS2DHODHNR3C1 | |
| SCHEMBL1689504 | 0.85 | SMO (0.45) | SSTR5SMODRD4DRD2DRD3 | |
| SCHEMBL5732275 | 0.84 | SSTR5 (0.45) | SSTR5PTGS1PTGS2DHODHNR3C1 | |
| SCHEMBL5907390 | 0.84 | SSTR5 (0.42) | SSTR5PTGS1PTGS2DHODHSMO | |
| SCHEMBL7256608 | 0.84 | SSTR5 (0.42) | SSTR5SMODRD4DRD2DRD3 | |
| SCHEMBL5731419 | 0.84 | SSTR5 (0.39) | SSTR5PTGS1PTGS2DHODHNR3C1 | |
| SCHEMBL7256580 | 0.84 | SSTR5 (0.42) | SSTR5DHODHSMODRD4DRD2 | |
| SCHEMBL5731934 | 0.83 | SSTR5 (0.46) | SSTR5S1PR1SMODRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003031435-A1 | PYRAZOLE DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS | MERCK PATENT GMBH (DE) | 2003-04-17 | — | — | WO | claimed |