Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227102 | 0.87 | LMNA (0.44) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL5907390 | 0.86 | SSTR5 (0.42) | SSTR5DHODHSMODRD2DRD4 | |
| SCHEMBL7257441 | 0.86 | SSTR5 (0.42) | SSTR5DHODHSMODRD2DRD4 | |
| SCHEMBL1689504 | 0.86 | SMO (0.45) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7262116 | 0.86 | SMO (0.45) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7260439 | 0.85 | SSTR5 (0.46) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7256641 | 0.84 | SSTR5 (0.40) | SSTR5DHODHSMODRD2DRD4 | |
| SCHEMBL7256580 | 0.84 | SSTR5 (0.42) | SSTR5DHODHSMODRD2DRD4 | |
| SCHEMBL7256608 | 0.84 | SSTR5 (0.42) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7261185 | 0.84 | SMO (0.39) | SSTR5SMODRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264419-A1 | Substituted pyrazoles | MERCK PATENT GMBH (DE) | 2006-11-23 | — | — | US | disclosed |
| EP-1626967-A1 | SUBSTITUTED PYRAZOLES | MERCK PATENT GmbH (DE) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004089931-A1 | SUBSTITUTED PYRAZOLES | MERCK PATENT GMBH (DE) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264419-A1 | Substituted pyrazoles | HTR3A, HTR1A, HTR1D | SSTR5 97/4885DHODH 3663/4885TACR1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.