Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17541903 | 0.76 | MAPK1 (0.34) | CYP1A2 | |
| SCHEMBL27861743 | 0.74 | L3MBTL1 (0.32) | — | |
| SCHEMBL19565571 | 0.73 | LMNA (0.40) | — | |
| SCHEMBL27917374 | 0.66 | UGT2B7 (0.38) | CYP1A2 | |
| SCHEMBL8003858 | 0.64 | MAPK1 (0.35) | — | |
| SCHEMBL6201777 | 0.64 | ATM (0.46) | — | |
| SCHEMBL8003854 | 0.64 | MAPK1 (0.35) | — | |
| SCHEMBL2625619 | 0.63 | ALDH1A1 (0.46) | — | |
| SCHEMBL737022 | 0.61 | — | — | |
| SCHEMBL19747687 | 0.60 | MAPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328527-A1 | CEPHALOTAXANES, THEIR METHOD OF PREPARATION AND THEIR USE IN TREATMENT OF CANCERS, LEUKEMIAS, PARASITES INCLUDING THOSE RESISTANT TO USUAL CHEMOTHERAPEUTIC AGENTS AND AS REVERSAL AGENTS | Oncopharm Corporation (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032904-A1 | NEW CEPHALOTAXANES, THEIR METHOD OF PREPARATION AND THEIR USE IN TREATMENT OF CANCERS, LEUKEMIAS, PARASITES INCLUDING THUS RESISTANT TO USUAL CHEMOTHERAPEUTIC AGENTS AND AS REVERSAL AGENTS | ONCOPHARM CORPORATION (FR) | 2002-04-25 | — | — | WO | disclosed |