Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.54 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759054 | 1.00 | HINT1 (0.54) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 | |
| SCHEMBL25711923 | 0.92 | HINT1 (0.50) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL24680699 | 0.88 | HINT1 (0.54) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 | |
| SCHEMBL18759058 | 0.87 | ALDH1A1 (0.43) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 | |
| SCHEMBL7253950 | 0.86 | TYMP (0.49) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL7253951 | 0.86 | TYMP (0.49) | HINT1GSK3ARPS6KA3MAPK14NT5E | |
| SCHEMBL3893075 | 0.84 | POLB (0.54) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 | |
| SCHEMBL18769456 | 0.84 | POLB (0.54) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 | |
| SCHEMBL2775081 | 0.84 | POLB (0.54) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 | |
| SCHEMBL23352540 | 0.84 | POLB (0.54) | HINT1GSK3ARPS6KA3MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051881-A1 | SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |