Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HINT1 | P49773 | 4/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257443 | 0.87 | HINT1 (0.54) | ALDH1A1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL18759054 | 0.87 | HINT1 (0.54) | ALDH1A1HINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL18769167 | 0.83 | ALDH1A1 (0.64) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL25711923 | 0.79 | HINT1 (0.50) | HINT1GSK3ARPS6KA3MAPK14FUT5 | |
| SCHEMBL22757440 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL24258664 | 0.77 | LMNA (0.42) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8284676 | 0.77 | LMNA (0.56) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL7069026 | 0.76 | PRKAB2 (0.46) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL7054416 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL23982314 | 0.76 | HSP90B1 (0.52) | GSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066797-A1 | TRINUCLEOTIDE MRNA CAP ANALOGS | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| WO-2017066782-A1 | HYDROPHOBIC MRNA CAP ANALOGS | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |