Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993529 | 0.86 | MRGPRX4 (0.52) | MRGPRX4CFDGAAMAPK1ALDH1A1 | |
| SCHEMBL8621838 | 0.82 | MRGPRX4 (0.49) | MRGPRX4CFDMAPK1ALDH1A1KDM4E | |
| SCHEMBL6866159 | 0.80 | CFD (0.70) | MRGPRX4CFDGAAALDH1A1KDM4E | |
| SCHEMBL7205819 | 0.80 | CA2 (0.59) | ALDH1A1KDM4ECA5ACA1CA2 | |
| SCHEMBL14880664 | 0.80 | MAPT (0.48) | PKMGAAALDH1A1KDM4ECA5A | |
| SCHEMBL12837926 | 0.79 | MRGPRX4 (0.57) | MRGPRX4CFDGAAALDH1A1KDM4E | |
| SCHEMBL384685 | 0.79 | MRGPRX4 (0.57) | MRGPRX4CFDGAAALDH1A1KDM4E | |
| SCHEMBL7597341 | 0.79 | MRGPRX4 (0.57) | MRGPRX4CFDGAAALDH1A1KDM4E | |
| SCHEMBL27648786 | 0.79 | KLKB1 (0.65) | ALDH1A1KDM4EHPGDCA5ACA1 | |
| SCHEMBL31252031 | 0.78 | MRGPRX4 (0.59) | MRGPRX4CFDGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055857-A1 | A PROCESS FOR SYNTHESIS OF HETEROCYCLIC AMINOALKYL BENZAMIDES | FARMACEUTSKO-HEMIJSKA INDUSTRIJA 'ZDRAVLJE' (YU) | 2003-07-10 | — | — | WO | claimed |
| CN-112441960-B | Synthetic method of sulpiride | 常州康普药业有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-112441960-A | Synthetic method of sulpiride | 常州康普药业有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-105646294-A | Method for synthesizing 2-methoxy-5-sulfamoylmethyl benzoate | 苏州诚和医药化学有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105481733-A | Method for synthesizing 2-methoxy-5-aminosulfonylmethyl benzoate by one-step method | SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD | 2016-04-13 | — | — | CN | disclosed |
| CN-105481733-A | Method for synthesizing 2-methoxy-5-aminosulfonylmethyl benzoate by one-step method | SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD | 2016-04-13 | — | — | CN | disclosed |
| WO-2003055857-A1 | A PROCESS FOR SYNTHESIS OF HETEROCYCLIC AMINOALKYL BENZAMIDES | FARMACEUTSKO-HEMIJSKA INDUSTRIJA 'ZDRAVLJE' (YU) | 2003-07-10 | — | — | WO | disclosed |