Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133156 | 0.90 | SMN1; SMN2 (0.43) | TDP1L3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10703108 | 0.87 | TSHR (0.40) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL10700924 | 0.84 | LTA4H (0.45) | ALDH1A1SMN1; SMN2HIF1ASLC1A3SLC1A1 | |
| SCHEMBL4061223 | 0.83 | SIRT2 (0.44) | ALDH1A1TYR | |
| SCHEMBL10421087 | 0.83 | SLC1A1 (0.46) | SMN1; SMN2HIF1ASLC1A3SLC1A1LTA4H | |
| SCHEMBL149592 | 0.83 | ALDH1A1 (0.49) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL27864459 | 0.82 | LMNA (0.49) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL11011081 | 0.82 | LTA4H (0.50) | L3MBTL1ALDH1A1SMN1; SMN2HIF1ASLC1A3 | |
| SCHEMBL7266221 | 0.82 | ALDH1A1 (0.52) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL7266217 | 0.82 | ALDH1A1 (0.52) | TSHRTDP1L3MBTL1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777679-B1 | DELIVERY OF NUCLEIC ACIDS | COMMW SCIENT IND RES ORG (AU) | 2003-11-05 | — | — | EP | disclosed |
| US-5906922-A | EXPOSING THE CELL WITH A PEPTIDENUCLEIC ACID; USEFUL FOR DELIVERING DNA OR RNA | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-05-25 | — | — | US | disclosed |
| EP-0777679-A4 | DELIVERY OF NUCLEIC ACIDS | COMMW SCIENT IND RES ORG (AU) | 1997-10-08 | — | — | EP | disclosed |
| EP-0777679-A1 | DELIVERY OF NUCLEIC ACIDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005218-A1 | DELIVERY OF NUCLEIC ACIDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1996-02-22 | — | — | WO | disclosed |