SCHEMBL499291

SCHEMBL499291

Oc1ccc(C2=C3C=CC(=N3)C(c3ccc(O)cc3)=C3C=CC(=N3)C(c3ccc(O)cc3)=C3C=CC(=N3)C(c3ccc(O)cc3)=C3C=CC2=N3)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 8/20 0.42
▸ ESR2 Q92731 5/20 0.42
▸ SENP1 Q9P0U3 1/20 0.40
▸ MEN1 O00255 4/20 0.39
▸ KMT2A Q03164 4/20 0.39
▸ MAPT P10636 3/20 0.39
▸ NPC1 O15118 3/20 0.39
▸ RAB9A P51151 3/20 0.39
▸ NFKB1 P19838 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ NFKB2 Q00653 1/20 0.39
▸ RELA Q04206 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ RPS6KA3 P51812 1/20 0.36
▸ MMP3 P08254 1/20 0.36
▸ BCL2L1 Q07817 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049798 0.92 MMP3 (0.50) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL6292615 0.92 MMP3 (0.50) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL28865295 0.91 MMP3 (0.48) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL9582303 0.91 RPS6KA3 (0.43) ESR1ESR2SENP1MEN1KMT2A
SCHEMBL8179946 0.91 MMP3 (0.48) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL28436561 0.91 MMP3 (0.48) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL27864432 0.91 THRB (0.46) ESR1ESR2SENP1MEN1KMT2A
SCHEMBL22463700 0.86 CA2 (0.52) ESR2MEN1KMT2AMAPTRAB9A
SCHEMBL4410281 0.86 ESR2 (0.56) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL7258220 0.85 LMNA (0.53) SENP1SMN1; SMN2ALDH1A1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565426-B2 Photothermal catalytic method for production of hydrogen peroxide without sacrificial reagents on basis of porphyrin-based supermolecule JIANGNAN UNIVERSITY (CN) 2026-03-03 — — US claimed
US-20220340423-A1 Photothermal Catalytic Method for Production of Hydrogen Peroxide without Sacrificial Reagents on Basis of Porphyrin-based Supermolecule JIANGNAN UNIVERSITY (CN) 2022-10-27 — — US claimed
EP-1600766-B1 ACTIVE OXYGEN SPECIES MEASURING DEVICE YUASA MAKOTO (JP) 2019-06-26 — — EP claimed
US-9867800-B2 Method of quenching singlet and triplet excited states of pigments, such as porphyrin compounds, particularly protoporphyrin IX, with conjugated fused tricyclic compounds have electron withdrawing groups, to reduce generation of reactive oxygen species, particularly singlet oxygen HALLSTAR INNOVATIONS CORP. (US) 2018-01-16 — — US claimed
US-20180000753-A1 EUTECTIC SOLVENTS AND USES THEREOF UNIVERSITY OF OSLO (NO) 2018-01-04 — — US claimed
WO-2016108083-A1 EUTECTIC SOLVENTS AND USES THEREOF UNIVERSITY OF OSLO (NO) 2016-07-07 — — WO claimed
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN HALLSTAR INNOVATIONS CORP. (US) 2015-06-18 — — US claimed
WO-2014025370-A1 TRICYCLIC ENERGY QUENCHER COMPOUNDS FOR REDUCING SINGLET OXYGEN GENERATION HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 — — WO claimed
US-8298387-B2 Reactive oxygen species measuring device YUASA MAKOTO (JP) 2012-10-30 — — US claimed
US-20060289313-A1 Reactive oxygen species measuring device YUASA MAKOTO 2006-12-28 — — US claimed
EP-1600766-A1 ACTIVE OXYGEN SPECIES MEASURING DEVICE Yuasa, Makoto (JP) 2005-11-30 — — EP claimed
US-12565426-B2 Photothermal catalytic method for production of hydrogen peroxide without sacrificial reagents on basis of porphyrin-based supermolecule JIANGNAN UNIVERSITY (CN) 2026-03-03 — — US disclosed
WO-2025047802-A1 JUNCTION PHOTOCATALYST 花王株式会社 2025-03-06 — — WO disclosed
US-12071498-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2024-08-27 — — US disclosed
US-20240115508-A1 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS THE JOHNS HOPKINS UNIVERSITY 2024-04-11 — — US disclosed
EP-0336879-A1 Meso-tetraphenylporphyrin complex compounds,process for their preparation and pharmaceuticals containing them SCHERING AKTIENGESELLSCHAFT (DE) 1989-10-11 — — EP disclosed
US-4837221-A ADMINISTERING PORPHYRIN DERIVATIVE TO LOCATE TUMOR, ILLUMINATING WITH LIGHT EFAMOL LTD. (GB) 1989-06-06 — — US disclosed
EP-0186962-B1 PORPHYRINS AND CANCER TREATMENT EFAMOL LIMITED (GB) 1989-04-12 — — EP disclosed
EP-0214839-A2 Improvements in relation to drug treatments EFAMOL HOLDINGS PLC (GB) 1987-03-18 — — EP disclosed
EP-0186962-A1 Porphyrins and cancer treatment EFAMOL LIMITED (GB) 1986-07-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565426-B2 Photothermal catalytic method for production of hydrogen peroxide without sacrificial reagents on basis of porphyrin-based supermolecule TPO, PPOX, THPO ESR1 4540/4885ESR2 4527/4885SENP1 327/4885
US-20240115508-A1 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS MUC1, SLC35A1, EPCAM ESR1 2315/4885ESR2 2773/4885SENP1 4318/4885
US-20150164852-A1 METHOD OF QUENCHING SINGLET AND TRIPLET EXCITED STATES OF PIGMENTS, SUCH AS PORPHYRIN COMPOUNDS, PARTICULARLY PROTOPORPHYRIN IX, WITH CONJUGATED FUSED TRICYCLIC COMPOUNDS HAVE ELECTRON WITHDRAWING GROUPS, TO REDUCE GENERATION OF REACTIVE OXYGEN SPECIES, PARTICULARLY SINGLET OXYGEN NOX3, CBR3, CCR3 ESR1 2195/4885ESR2 1456/4885SENP1 4656/4885
US-20180000753-A1 EUTECTIC SOLVENTS AND USES THEREOF UROD, DUS2, ALAD ESR1 503/4885ESR2 671/4885SENP1 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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