Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262414 | 0.92 | ALDH1A1 (0.35) | RAB9ASMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL20562935 | 0.75 | TAAR1 (0.41) | RAB9ASMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL7262450 | 0.73 | KMT2A (0.45) | RAB9ASMN1; SMN2ALDH1A1NPC1HPGD | |
| SCHEMBL31663185 | 0.68 | LMNA (0.51) | SMN1; SMN2ALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL5786000 | 0.67 | ACHE (0.38) | SMN1; SMN2ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL7258443 | 0.66 | KMT2A (0.52) | SMN1; SMN2ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL20562383 | 0.65 | TAAR1 (0.56) | — | |
| SCHEMBL29828687 | 0.65 | TAAR1 (0.56) | — | |
| SCHEMBL4843143 | 0.64 | CYP3A4 (0.54) | RAB9ASMN1; SMN2ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL30639531 | 0.64 | TAAR1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067935-B1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1067935-A4 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1067935-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | The Regents of the University of California (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6124278-A | COGNITION ACTIVATORS FOR LEARNING/MEMORY ENHANCEMENT AND TREATMENT OF BRAIN/PSYCHOLOGICAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999051240-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-10-14 | — | — | WO | disclosed |