Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247923 | 0.75 | HPGD (0.51) | ALDH1A1TP53MEN1HPGDKMT2A | |
| SCHEMBL10985277 | 0.71 | METAP2 (0.46) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL437231 | 0.68 | ALDH1A1 (0.87) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL9375363 | 0.68 | RAB9A (0.46) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL10888615 | 0.68 | RAB9A (0.44) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL11266259 | 0.67 | ALDH1A1 (0.83) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL11266257 | 0.67 | ALDH1A1 (0.83) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL18250666 | 0.66 | PTPN1 (0.43) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL20512531 | 0.65 | TP53 (0.56) | RAB9AALDH1A1TP53MEN1HPGD | |
| SCHEMBL5475532 | 0.65 | ALDH1A1 (0.66) | RAB9AALDH1A1TP53MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007878-A2 | ANTIFUNGAL AGENTS OF SORDARIN DERIVATIVES | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |