Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559951 | 0.85 | ABCB11 (0.33) | KMT2AGAAKDM4E | |
| SCHEMBL9139695 | 0.84 | CES2 (0.42) | TSHRTHRBKMT2ACES2 | |
| SCHEMBL20561057 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TSHRTHRB | |
| SCHEMBL7560874 | 0.81 | KMT2A (0.35) | ALDH1A1TSHRTHRBKMT2ANPC1 | |
| SCHEMBL7258437 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL27547228 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL20561060 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBCES2 | |
| SCHEMBL13391772 | 0.72 | ALDH1A1 (0.43) | ALDH1A1TSHRTHRBHPGDNPC1 | |
| SCHEMBL9937107 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TSHRTHRBKMT2AHPGD | |
| SCHEMBL27009189 | 0.69 | TSHR (0.39) | ALDH1A1TSHRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0965335-B1 | Metered-dose aerosol formulations | MINNESOTA MINING & MFG (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-0965335-A1 | Metered-dose aerosol formulations | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0636362-B1 | The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations | MINNESOTA MINING & MFG (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0526481-B1 | THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS | MINNESOTA MINING & MFG (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0636362-A2 | The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-01 | — | — | EP | disclosed |