SCHEMBL7560874

SCHEMBL7560874

CCOC(F)(F)C(=O)OC

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 4/20 0.33
GAA P10253 2/20 0.33
DGAT1 O75907 1/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
LMNA P02545 1/20 0.32
PKM P14618 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 2/20 0.31
THRB P10828 1/20 0.31
KCNN4 O15554 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7258372 0.81 ALDH1A1 (0.41) KMT2AALDH1A1GAASMN1; SMN2KDM4E
SCHEMBL27009189 0.77 TSHR (0.39) KMT2AALDH1A1GAADGAT1MGAM
SCHEMBL11659311 0.77 LMNA (0.36) KMT2AALDH1A1GAADGAT1MGAM
SCHEMBL13698708 0.76 ALOX15 (0.30) GAAMGAMSIMGAM2
SCHEMBL16658462 0.76 DGAT1 (0.34) ALDH1A1GAADGAT1MGAMSI
SCHEMBL15951338 0.75 MGAM (0.36) ALDH1A1GAADGAT1MGAMSI
SCHEMBL7563376 0.75
SCHEMBL9017248 0.75
SCHEMBL17487351 0.75
SCHEMBL19300076 0.74 DGAT1 (0.39) KMT2AALDH1A1GAADGAT1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638112-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2002-08-07 EP disclosed
EP-0792255-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2001-02-28 EP disclosed
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed
US-5482650-A Liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-09 US disclosed
US-5437812-A Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-01 US disclosed
EP-0638112-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-15 EP disclosed
US-5262082-A Ferroelectric liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
WO-1993022396-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-11 WO disclosed
US-4343742-A CYCLIZATION OF MONOETHERS CONTAINING CARBONYL, AMMONIUM OR ALKALI FLUORIDE HOECHST AKTIENGESELLSCHAFT 1982-08-10 US disclosed