SCHEMBL7258451

SCHEMBL7258451

OCOc1ccccc1-c1nc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.50
L3MBTL1 Q9Y468 4/20 0.49
TDP1 Q9NUW8 2/20 0.49
LMNA P02545 4/20 0.48
MAPK1 P28482 3/20 0.48
ALOX15 P16050 2/20 0.48
TSHR P16473 2/20 0.48
GAA P10253 1/20 0.48
ADORA3 P0DMS8 1/20 0.46
ADORA2A P29274 1/20 0.46
ADORA2B P29275 1/20 0.46
ADORA1 P30542 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
TP53 P04637 1/20 0.45
RAB9A P51151 1/20 0.45
MAOA P21397 2/20 0.43
HTR7 P34969 1/20 0.42
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581724 0.88 MAPK1 (0.51) MAOBL3MBTL1TDP1LMNAMAPK1
SCHEMBL8733676 0.83 MAPK1 (0.60) L3MBTL1TDP1LMNAMAPK1RXRA
SCHEMBL8918201 0.83 MAPK1 (0.46) MAOBL3MBTL1TDP1LMNAMAPK1
SCHEMBL18617549 0.77 TDP1 (0.46) L3MBTL1TDP1LMNAMAPK1GAA
SCHEMBL21922946 0.75 L3MBTL1 (0.56) L3MBTL1LMNAMAPK1ALOX15TSHR
SCHEMBL16246145 0.74 L3MBTL1 (0.61) L3MBTL1LMNAMAPK1ALOX15TSHR
SCHEMBL22329445 0.74 NCOA1 (0.59) MAOBL3MBTL1TDP1LMNAMAPK1
SCHEMBL17720964 0.73 L3MBTL1 (0.54) L3MBTL1LMNAMAPK1ALOX15TSHR
SCHEMBL12854006 0.73 L3MBTL1 (0.54) L3MBTL1LMNAMAPK1ALOX15TSHR
SCHEMBL19497486 0.72 L3MBTL1 (0.58) L3MBTL1LMNAMAPK1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030207969-A1 Flame retardant compositions CAPOCCI GERALD A (US) 2003-11-06 US disclosed