Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482197 | 0.83 | ABCC9 (0.50) | SMN1; SMN2GAATDP1HTT | |
| SCHEMBL482195 | 0.83 | ABCC9 (0.50) | SMN1; SMN2GAATDP1HTT | |
| SCHEMBL4773615 | 0.83 | ABCC9 (0.50) | SMN1; SMN2GAATDP1HTT | |
| SCHEMBL7870442 | 0.82 | KCNE1 (0.36) | — | |
| SCHEMBL6931951 | 0.81 | KCNE1 (0.54) | SIGMAR1MAPTTSHRALDH1A1MEN1 | |
| SCHEMBL9876498 | 0.81 | KCNE1 (0.39) | MAPTTSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6935375 | 0.79 | KCNE1 (0.57) | HTR2BSIGMAR1TMEM97SMN1; SMN2ALDH1A1 | |
| SCHEMBL5868353 | 0.79 | IDO1 (0.40) | HTR2BSIGMAR1HTR1AMAPTHTR2C | |
| SCHEMBL5868357 | 0.79 | IDO1 (0.40) | HTR2BSIGMAR1HTR1AMAPTHTR2C | |
| SCHEMBL6274078 | 0.79 | IDO1 (0.40) | HTR2BSIGMAR1HTR1AMAPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003014113-A1 | NOVEL BENZOPYRAN COMPOUNDS AND PROCESS FOR THEIR PREPARATION AND USE | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2003-02-20 | — | — | WO | disclosed |