Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 5/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258457 | 0.81 | HTR2B (0.41) | MAPTSMN1; SMN2TSHRALDH1A1MEN1 | |
| SCHEMBL482263 | 0.78 | ABCC9 (0.49) | MAPTCNR2ALDH1A1CNR1RAB9A | |
| SCHEMBL4715927 | 0.78 | ABCC9 (0.49) | MAPTCNR2ALDH1A1CNR1RAB9A | |
| SCHEMBL482265 | 0.78 | ABCC9 (0.49) | MAPTCNR2ALDH1A1CNR1RAB9A | |
| SCHEMBL7870442 | 0.77 | KCNE1 (0.36) | KCNE1KCNQ1 | |
| SCHEMBL6935375 | 0.76 | KCNE1 (0.57) | KCNE1KCNQ1SMN1; SMN2HIF1AALDH1A1 | |
| SCHEMBL7693611 | 0.76 | KDM4E (0.41) | — | |
| SCHEMBL7048877 | 0.76 | KDM4E (0.41) | — | |
| SCHEMBL6931951 | 0.76 | KCNE1 (0.54) | KCNE1KCNQ1MAPTTSHRALDH1A1 | |
| SCHEMBL10956358 | 0.76 | ALOX5 (0.45) | SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |