Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262972 | 0.88 | HSD17B1 (0.33) | ADAHSD17B1HSD17B2DYRK3MAP4K4 | |
| SCHEMBL7258881 | 0.88 | ADA (0.39) | ADADYRK3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL7263018 | 0.87 | ADA (0.41) | ADAHSD17B1HSD17B2DYRK3MAP4K4 | |
| SCHEMBL7258788 | 0.81 | CHEK2 (0.39) | ADADYRK3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL7258984 | 0.81 | CHEK2 (0.41) | ADAHSD17B1HSD17B2MKNK2CHEK2 | |
| SCHEMBL7259601 | 0.80 | ADA (0.44) | ADAKDM4EALDH1A1LMNAHTT | |
| SCHEMBL7258931 | 0.80 | HSD17B1 (0.32) | ADAHSD17B1HSD17B2DYRK3MAP4K4 | |
| SCHEMBL7259458 | 0.79 | ADA (0.40) | ADADYRK3MAP4K4PIM1RPS6KB1 | |
| SCHEMBL7264346 | 0.79 | ATP4A (0.38) | ADAGAAKDM4EALDH1A1LMNA | |
| SCHEMBL7258942 | 0.77 | ADA (0.43) | ADACHEK2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |